Johnson & Johnson and Pharmacyclics Inc. won U.S. approval for their breakthrough therapy to treat a rare blood cancer, becoming the second drug to gain marketing clearance under the process created to speed new medicines to seriously ill patients.
Aveo Pharmaceuticals Inc. failed to win the backing of U.S. regulatory advisers for its lead product candidate, a kidney cancer drug, after the panelists questioned whether it was as effective as existing treatments.
Roche Holding AG’s Perjeta won expanded U.S. approval as the first pre-surgical therapy in breast cancer, increasing the odds the disease may be stopped in those diagnosed with early stage HER2-positive tumors.
Bristol-Myers Squibb Co. won U.S. approval for ipilimumab, the first drug proven to extend the lives of patients with advanced melanoma, the most deadly form of skin cancer. The shares rose the most in nine months.